
Lactobacillus plantarum DR7 -
Alleviates Stress & Anxiety

Anxiety is a common disorder in our modern lifestyles and can be triggered by stress, aging and obesity.
​
In 111 stressed adults (DR7 n=56, placebo n=55), the consumption of Lactobacillus plantarum DR7 (1×109 cfu/day) for 12 weeks reduced symptoms of stress (P=0.024), anxiety (P=0.017), and total psychological scores(P=0.022) as early as 8 weeks among stressed adults compared to the placebo group as assessed by the DASS-42 questionnaire. DASS-42 comprises of 42 item self-report validated inventory including three scales designed to measure the negative emotional states of depression, anxiety and stress, where each of the three scales contained 14 questions.
(A)

(B)

(C)

Figure 2: Effects of a 12-week administration of Lactobacillus plantarum DR7 or placebo, on changes in scores as compared to week 0 for (A) Stress, (B) Anxiety, (C) Total scores DASS-42 in all subjects. P-values indicated difference between treatment groups at individual time points. Results are expressed as mean; error bars (SEM); n=111 (DR7 n=56, placebo n=55).
​
(Chong et al., Beneficial Microbes, 2019)